CSNK2A1/CK II alpha antibody

Catalog No. ABIN498273

Product Details anti-CSNK2A1/CK II alpha Antibody

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK2A1/CK II alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of CKII-α protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Purity: > 95 % (by SDS-PAGE)

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Alternative Name: Casein Kinase II Subunit alpha (CSNK2A1 Products)

Synonyms: CK2A2 antibody, CSNK2A1 antibody, CK2A1 antibody, CKII antibody, CSNK2A3 antibody, CK2A antibody, Ck2a antibody, BmCK2a antibody, wu:fi38e04 antibody, wu:fi38h03 antibody, csnk2a1 antibody, CK-II antibody, CK2 antibody, Ckiialpha antibody, Csnk2a1-rs4 antibody, ck2a1 antibody, casein kinase 2 alpha 2 antibody, casein kinase 2 alpha 1 antibody, casein kinase 2 alpha subunit antibody, casein kinase 2, alpha 1 polypeptide antibody, CK2 protein kinase alpha 2 antibody, casein kinase II alpha subunit antibody, Casein kinase II alpha subunit antibody, casein kinase 2, alpha 1 polypeptide S homeolog antibody, CSNK2A2 antibody, CSNK2A1 antibody, ck2a antibody, Ck2a antibody, csnk2a1 antibody, cka2 antibody, Ckiialpha antibody, CK2A1 antibody, Csnk2a1 antibody, csnk2a1.S antibody

Background: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, e and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CK II alpha, CK2A1, CSNK2A1

Molecular Weight: approx. 45 kDa

Gene ID: 1457

NCBI Accession: NP_001886

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interactome