ELL antibody

Catalog No. ABIN498288

Product Details anti-ELL Antibody

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of ELL protein. (region surrounding Asp125)

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Alternative Name: ELL (ELL Products)

Synonyms: wu:fc60b11 antibody, zgc:63836 antibody, C19orf17 antibody, ELL1 antibody, MEN antibody, PPP1R68 antibody, Ell1 antibody, Men antibody, elongation factor for RNA polymerase II antibody, elongation factor RNA polymerase II antibody, ELL antibody, ell antibody, Ell antibody

Background: ELL was shown to encode an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL is the second elongation factor to be implicated in oncogenesis.Synonyms: C19orf17, Eleven-nineteen lysine-rich leukemia protein, RNA polymerase II elongation factor ELL

Molecular Weight: approx. 65 kDa

Gene ID: 8178

NCBI Accession: NP_006523

UniProt: P55199