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RFC3 antibody

RFC3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN498529
  • Target See all RFC3 Antibodies
    RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
    Reactivity
    • 35
    • 18
    • 16
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 29
    • 6
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFC3 antibody is un-conjugated
    Application
    • 27
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of RFC3 protein. (region surrounding Leu227)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography using epitope-specific immunogen
    Purity
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product RFC3 Primary Antibody
  • Application Notes
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
    Alternative Name
    RFC3 / RFC38 (RFC3 Products)
    Synonyms
    CG5313 antibody, DRFC antibody, DmRFC3 antibody, Dmel\\CG5313 antibody, Rfc3 antibody, 21.m02902 antibody, 2810416I22Rik antibody, 38kDa antibody, AU022547 antibody, Recc3 antibody, cb275 antibody, RFC38 antibody, Replication factor C subunit 3 antibody, replication factor C3 antibody, replication factor C subunit 3 antibody, replication factor C 38 kDa subunit antibody, DNA replication factor C complex subunit Rfc3 antibody, replication factor C3, putative antibody, replication factor C (activator 1) 3 antibody, replication factor C subunit 3 L homeolog antibody, RfC3 antibody, PF14_0601 antibody, Chro.30359 antibody, PB000006.01.0 antibody, PC000345.04.0 antibody, TP04_0380 antibody, Tb09.211.3310 antibody, PY04255 antibody, PVX_117300 antibody, BBOV_IV003080 antibody, SJAG_02182 antibody, PKH_124240 antibody, rfc3 antibody, Rfc3 antibody, RFC3 antibody, rfc3.L antibody
    Background
    The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: Activator 1 38 kDa subunit, Activator 1 subunit 3, RF-C 38 kDa subunit, Replication factor C 38 kDa subunit, Replication factor C subunit 3
    Molecular Weight
    approx. 41 kDa
    Gene ID
    5983
    NCBI Accession
    NP_002906
    UniProt
    P40938
    Pathways
    Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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