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MAPK14 antibody
MAPK14
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAPK14 Antibody
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Target
See all MAPK14 Antibodies
MAPK14
(Mitogen-Activated Protein Kinase 14 (MAPK14))
Reactivity
All reactivities for MAPK14 antibodies
Human, Mouse, Rat
Host
All hosts for MAPK14 antibodies
Rabbit
Clonality
All clonalities for MAPK14 antibodies
Polyclonal
Conjugate
All conjugates for MAPK14 antibodies
This MAPK14 antibody is un-conjugated
Application
All applications for MAPK14 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects endogenous levels of p38 protein. (region surrounding Thr175)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Purity
> 95 % pure SDS-PAGE
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Discover our top product MAPK14 Primary Antibody
Alternatives
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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 141-240) antibody
MAPK14
Reactivity: Human, Mouse, Rat, Rabbit
WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MAPK14
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Target
MAPK14
(Mitogen-Activated Protein Kinase 14 (MAPK14))
Alternative Name
MAP Kinase p38 alpha / MAPK14 (MAPK14 Products )
Synonyms
CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB1 antibody, EXIP antibody, Mxi2 antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK2A antibody, p38 antibody, p38ALPHA antibody, CRK1 antibody, Csbp1 antibody, Csbp2 antibody, Exip antibody, Hog antibody, Prkm14 antibody, Prkm15 antibody, Sapk2A antibody, p38Hog antibody, p38alpha antibody, p38b antibody, zp38b antibody, MAPK14 antibody, 186F5S antibody, BG:DS00797.3 antibody, CG7393 antibody, D-p38 antibody, D-p38 MAPK antibody, D-p38b antibody, Dm p38b antibody, Dmel\\CG7393 antibody, Dmp38b antibody, Dp38 antibody, Dp38b antibody, ESTS:186F5S antibody, Mpk34C antibody, anon-sts23 antibody, dp38b antibody, p38 MAPK antibody, p38 beta antibody, p38B antibody, p38Kb antibody, p38beta antibody, Crk1 antibody, p38-alpha antibody, p38MAPK antibody, p38a antibody, csbp antibody, mapk14a antibody, mxi2 antibody, sapk2 antibody, sapk2a antibody, AP22.98 antibody, AP22_98 antibody, ATMPK14 antibody, mitogen-activated protein kinase 14 antibody, SAPK2a antibody, MAP kinase 14A antibody, MAP kinase p38a antibody, MAPK 14A antibody, fk28c03 antibody, hm:zeh1243 antibody, wu:fk28c03 antibody, zp38a antibody, P38C-CRK antibody, mitogen-activated protein kinase 14 antibody, mitogen activated protein kinase 14 antibody, mitogen-activated protein kinase 14b antibody, p38b MAP kinase antibody, mitogen-activated protein kinase 14 S homeolog antibody, mitogen-activated protein kinase 14a antibody, CRK proto-oncogene, adaptor protein antibody, MAPK14 antibody, Mapk14 antibody, mapk14b antibody, p38b antibody, mapk14.S antibody, MPK14 antibody, mapk14a antibody, CRK antibody
Background
MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation.Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha
Molecular Weight
approx. 43 kDa
Gene ID
1432
NCBI Accession
NP_001306
UniProt
Q16539
Pathways
MAPK Signaling , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Muscle Cell Differentiation , Regulation of Cell Size , Hepatitis C , Toll-Like Receptors Cascades , Autophagy , Thromboxane A2 Receptor Signaling , BCR Signaling , S100 Proteins
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