CD69 antibody
-
- Target See all CD69 Antibodies
- CD69
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CD69 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Specificity
- This antibody detects endogenous levels of CD69 protein. (region surrounding Arg134)
- Cross-Reactivity (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product CD69 Primary Antibody
-
-
- Application Notes
-
Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- CD69
- Alternative Name
- CD69 (CD69 Products)
- Synonyms
- 5830438K24Rik antibody, AI452015 antibody, AIM antibody, VEA antibody, BL-AC/P26 antibody, CLEC2C antibody, EA1 antibody, GP32/28 antibody, MLR-3 antibody, Cd69 molecule antibody, CD69 antigen antibody, CD69 molecule antibody, Cd69 antibody, CD69 antibody
- Background
- CD69 is a disulfide linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C type lectin, most closely related to the NKRP1 and Ly49 NK cell activation molecules. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. It is the earliest inducible cell surface glycoprotein acquired during lymphoid activation. Induction occurs by antigens, mitogens or activators of PKC on the surface of T and B lymphocytes, and by interaction of IL2 with the p75 IL2R on the surface of NK cells. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.Synonyms: AIM, Activation inducer molecule, BL-AC/P26, C-type lectin domain family 2 member C, EA1, Early T-cell activation antigen p60, Early activation antigen CD69, GP32/28, Leu-23, MLR-3
- Molecular Weight
- approx. 23 kDa
- Gene ID
- 969
- NCBI Accession
- NP_001772
- UniProt
- Q07108
-