PLA2G6 antibody (AA 651-750) (Alexa Fluor 680)
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- Target See all PLA2G6 Antibodies
- PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))
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Binding Specificity
- AA 651-750
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLA2G6 antibody is conjugated to Alexa Fluor 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CaI-PLA2/PLA2G6
- Isotype
- IgG
- Top Product
- Discover our top product PLA2G6 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))
- Alternative Name
- CaI-PLA2 (PLA2G6 Products)
- Synonyms
- zgc:77476 antibody, wu:fc06g09 antibody, PNPLA9 antibody, MGC83523 antibody, PLA2G6 antibody, BB112799 antibody, iPLA(2)beta antibody, iPLA2 antibody, iPLA2beta antibody, CaI-PLA2 antibody, GVI antibody, INAD1 antibody, IPLA2-VIA antibody, NBIA2 antibody, NBIA2A antibody, NBIA2B antibody, PARK14 antibody, PLA2 antibody, iPla2 antibody, phospholipase A2, group VI (cytosolic, calcium-independent) antibody, phospholipase A2 group VI antibody, phospholipase A2 group VI S homeolog antibody, 85/88 kDa calcium-independent phospholipase A2 antibody, phospholipase A2, group VI antibody, pla2g6 antibody, PLA2G6 antibody, pla2g6.S antibody, LOC100445065 antibody, Pla2g6 antibody
- Background
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Synonyms: GVI, PLA2, INAD1, NBIA2, iPLA2, NBIA2A, NBIA2B, PARK14, PNPLA9, CaI-PLA2, IPLA2-VIA, iPLA2beta, 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PLA2G6, PLPLA9
Background: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
- Gene ID
- 8398
- UniProt
- O60733
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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