FAM161B antibody (AA 451-560) (AbBy Fluor® 680)
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- Target See all FAM161B products
- FAM161B (Family with Sequence Similarity 161, Member B (FAM161B))
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Binding Specificity
- AA 451-560
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAM161B antibody is conjugated to AbBy Fluor® 680
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FAM161B
- Isotype
- IgG
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FAM161B (Family with Sequence Similarity 161, Member B (FAM161B))
- Alternative Name
- FAM161B (FAM161B Products)
- Synonyms
- C14orf44 antibody, c14_5547 antibody, 9330169D17 antibody, 9830169C18Rik antibody, RGD1309058 antibody, family with sequence similarity 161 member B antibody, family with sequence similarity 161, member B antibody, FAM161B antibody, Fam161b antibody
- Background
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Synonyms: C14orf44, Chromosome 14 open reading frame 44, Family with sequence similarity 161, member B, FLJ31697, Hypothetical protein LOC145483, Protein FAM161B, F161B_HUMAN.
Background: FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer?s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder 1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.
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