CD235b/GYPB antibody (AA 21-91) (AbBy Fluor® 680)
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- Target See all CD235b/GYPB (GYPB) Antibodies
- CD235b/GYPB (GYPB) (Glycophorin B (GYPB))
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Binding Specificity
- AA 21-91
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD235b/GYPB antibody is conjugated to AbBy Fluor® 680
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Glycophorin B
- Isotype
- IgG
- Top Product
- Discover our top product GYPB Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD235b/GYPB (GYPB) (Glycophorin B (GYPB))
- Alternative Name
- GYPB (GYPB Products)
- Synonyms
- CD235b antibody, GPB antibody, GPB.NY antibody, GYPHe.NY antibody, GpMiIII antibody, HGpMiIII antibody, HGpMiVI antibody, HGpMiX antibody, MNS antibody, PAS-3 antibody, SS antibody, glycophorin B (MNS blood group) antibody, GYPB antibody
- Background
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Synonyms: SS, GPB, MNS, PAS-3, CD235b, GPB.NY, HGpMiX, GpMiIII, HGpMiVI, GYPHe.NY, HGpMiIII, Glycophorin-B, SS-active sialoglycoprotein, Sialoglycoprotein delta, GYPB
Background: Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains seven exons which are 97 % homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.
- Gene ID
- 2994
- UniProt
- P06028
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