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14-3-3 zeta antibody (AA 30-235)
YWHAZ
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-14-3-3 zeta Antibody
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Target
See all 14-3-3 zeta (YWHAZ) Antibodies
14-3-3 zeta (YWHAZ)
Binding Specificity
All epitopes for 14-3-3 zeta antibodies
AA 30-235
Reactivity
All reactivities for 14-3-3 zeta antibodies
Human
Host
All hosts for 14-3-3 zeta antibodies
Rabbit
Clonality
All clonalities for 14-3-3 zeta antibodies
Polyclonal
Conjugate
All conjugates for 14-3-3 zeta antibodies
This 14-3-3 zeta antibody is un-conjugated
Application
All applications for 14-3-3 zeta antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant 14-3-3 Zeta protein (amino acids 30-235) was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1-2 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for 14-3-3 zeta
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Target
14-3-3 zeta (YWHAZ)
Alternative Name
14-3-3 Zeta (YWHAZ Products )
Synonyms
14-3-3-zeta antibody, KCIP-1 antibody, YWHAD antibody, 14-3-3zeta antibody, Ywhaz antibody, ACYPI003154 antibody, 14-3-3z antibody, kcip-1 antibody, ywhaq antibody, 1433z antibody, ywhaz antibody, ywhazb antibody, 1110013I11Rik antibody, AI596267 antibody, AL022924 antibody, AU020854 antibody, ywhaza antibody, fb14h09 antibody, wu:fb05g08 antibody, wu:fb14h09 antibody, ywhai antibody, zgc:55807 antibody, 14-3-3 antibody, 14-3-3 zeta antibody, 14-3-3ZETA antibody, 14-3-3leo antibody, 2G1 antibody, 4-3-3 zeta antibody, 5.11 antibody, 549 antibody, BEST:GH05075 antibody, CG17870 antibody, D14-3-3 antibody, D14-3-3zeta antibody, Dmel\\CG17870 antibody, K antibody, LEO antibody, Leo antibody, PAR-5 antibody, PAR5 antibody, Par-5 antibody, d14-3-3zeta antibody, l(2)07103 antibody, l(2)46CFe antibody, l(2)46Ee antibody, leo antibody, par-5 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta antibody, 14-3-3 protein zeta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta L homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta S homeolog antibody, 14-3-3 protein zeta/delta pseudogene antibody, CG17870 gene product from transcript CG17870-RE antibody, YWHAZ antibody, 14-3-3zeta antibody, ywhaz antibody, 1433z antibody, ywhaz.L antibody, Ywhaz antibody, ywhaz.S antibody, LOC100855903 antibody
Background
14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer).
Molecular Weight
28 kDa
Gene ID
7534
UniProt
P63104
Pathways
Apoptosis , Hormone Transport , Myometrial Relaxation and Contraction , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Synaptic Membrane , Production of Molecular Mediator of Immune Response , Maintenance of Protein Location
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