LSD1 antibody (AA 97-328)

Catalog No. ABIN5027337

Product Details anti-LSD1 Antibody

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Binding Specificity: AA 97-328

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant LSD1 protein (amino acids 97-328) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 0.5-2.0 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Alternative Name: LSD1 (KDM1A Products)

Synonyms: AOF2 antibody, BHC110 antibody, KDM1 antibody, LSD1 antibody, 1810043O07Rik antibody, AA408884 antibody, Aof2 antibody, D4Ertd478e antibody, Kdm1 antibody, Lsd1 antibody, mKIAA0601 antibody, DKFZp459N2450 antibody, RGD1562975 antibody, aof2 antibody, kdm1 antibody, wu:fb82e06 antibody, wu:fc51a02 antibody, wu:fj36a05 antibody, wu:fj66b06 antibody, KDM1A antibody, lsd1 antibody, xLSD1 antibody, AtLSD1 antibody, F9F13.30 antibody, F9F13_30 antibody, LESION SIMULATING DISEASE antibody, LESION SIMULATING DISEASE 1 antibody, lysine demethylase 1A antibody, lysine (K)-specific demethylase 1A antibody, lysine (K)-specific demethylase 1a antibody, LSD1 zinc finger family protein antibody, KDM1A antibody, Kdm1a antibody, kdm1a antibody, LSD1 antibody

Background: LSD1 or KDM1A (lysine (K)-specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.

Molecular Weight: 115 kDa

Gene ID: 23028

UniProt: O60341

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect