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CD20 antibody

MS4A1 Reactivity: Human FACS, WB Host: Mouse Monoclonal ABM46C7 unconjugated
Catalog No. ABIN5027466
  • Target See all CD20 (MS4A1) Antibodies
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    Reactivity
    • 243
    • 57
    • 23
    • 18
    • 17
    • 16
    • 11
    • 7
    • 6
    • 4
    • 2
    • 1
    Human
    Host
    • 179
    • 91
    • 2
    • 2
    Mouse
    Clonality
    • 194
    • 78
    • 1
    Monoclonal
    Conjugate
    • 102
    • 20
    • 16
    • 13
    • 12
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD20 antibody is un-conjugated
    Application
    • 205
    • 90
    • 75
    • 46
    • 46
    • 28
    • 25
    • 16
    • 16
    • 14
    • 14
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    • 11
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    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB)
    Purification
    Protein G Chromatography
    Immunogen
    A partial length recombinant protein corresponding to extra cellular domain of CD20 was used as the immunogen for this antibody.
    Clone
    ABM46C7
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product MS4A1 Primary Antibody
  • Application Notes
    WB: 2-4 μg/mL FACS : 0.5 μg / 10^6 cells
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
    Alternative Name
    CD20 (MS4A1 Products)
    Synonyms
    B1 antibody, Bp35 antibody, CD20 antibody, CVID5 antibody, LEU-16 antibody, MS4A2 antibody, S7 antibody, AA960661 antibody, Cd20 antibody, Ly-44 antibody, Ms4a2 antibody, MS4A1 antibody, bp35 antibody, cd20 antibody, ms4a2 antibody, leu-16 antibody, ms4a4c antibody, cd20-like antibody, membrane spanning 4-domains A1 antibody, membrane-spanning 4-domains, subfamily A, member 1 antibody, B-lymphocyte antigen CD20 antibody, MS4A1 antibody, Ms4a1 antibody, ms4a1 antibody, LOC101694281 antibody
    Background
    CD20 is clinically validated as an immunotherapy target for B-cell lymphomas and autoimmune diseases. CD20 consists of large, intracellular, amino- and carboxyterminal portions connected by 4 membrane-spanning domains. Its high expression on malignant B cells and its reported lack of shedding from the surfacemake CD20 an ideal target for antibody-mediated killing. Anti-CD20 antibodies are believed to mediate the therapeutic effect by activation of complement-dependent cytotoxicity (CDC) and largely by antibody-dependent cellular cytotoxicity exerted by recruitment of innate immune effector cells expressing the Fcgamma receptor IIIa.
    Molecular Weight
    32 kDa
    Gene ID
    931
    UniProt
    P11836
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