TNFSF15 antibody

Catalog No. ABIN5067734

Product Details anti-TNFSF15 Antibody

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFSF15 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Vascular endothelial cell growth inhibitor (VEGI), a member of the tumor necrosis factor (TNF) family, is an endothelial cell-specific inhibitor of angiogenesis. Overexpression of a secretable VEGI fusion protein by cancer cells resulted in abrogation of xenograft tumor progression. 4-3H8B is a mouse monoclonal IgG1 raised against a recombinant VEGI isoform which shares a C-terminal 151-residue segment with previously reported VEGI with 174 residues.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: recombinant VEGI isoforms

Clone: 4-3H8B

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for TNFSF15

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Alternative Name: VEGI (TNFSF15 Products)

Synonyms: TTPAL antibody, TL1 antibody, TL1A antibody, VEGI antibody, VEGI192A antibody, Tl1 antibody, Tl1a antibody, Vegi antibody, tumor necrosis factor superfamily member 15 antibody, TNF superfamily member 15 antibody, tumor necrosis factor (ligand) superfamily, member 15 antibody, TNFSF15 antibody, Tnfsf15 antibody

Background: Vascular endothelial cell growth inhibitor (VEGI), a member of the tumor necrosis factor (TNF) family, is an endothelial cell-specific inhibitor of angiogenesis. Overexpression of a secretable VEGI fusion protein by cancer cells resulted in abrogation of xenograft tumor progression. 4-3H8B is a mouse monoclonal IgG1 raised against a recombinant VEGI isoform which shares a C-terminal 151-residue segment with previously reported VEGI with 174 residues.

UniProt: O95150

Pathways: Positive Regulation of Endopeptidase Activity, Autophagy