NFKBIA antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha)

Details for Product anti-NFKBIA Antibody No. ABIN531958
Antigen
Reactivity
Human
477
301
244
31
24
20
19
9
2
2
2
1
1
Host
Mouse
422
60
7
7
Clonality (Clone)
Monoclonal ()
Conjugate
This NFKBIA antibody is un-conjugated
27
13
13
13
13
13
13
12
10
6
6
6
3
3
3
3
3
Application
Immunoprecipitation (IP), Western Blotting (WB)
356
183
156
78
76
59
41
28
19
18
14
4
4
3
3
3
1
1
1
Options
Purpose Mouse monoclonal antibody raised against partial recombinant NFKBIA .
Immunogen Recombinant protein corresponding to amino acids 32-291 of human NFKBIA.
Clone 6A920
Isotype IgG1
Cross-Reactivity Mouse (Murine)
Antigen
Alternative Name NFKBIA / IKBA (NFKBIA Antibody Abstract)
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades
Application Notes The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.05 % BSA, 0.05 % sodium azide)
Storage 4 °C,-20 °C
Storage Comment Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Supplier Images
Image no. 1 for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibody (ABIN531958) Jurkat cells were treated for 30 min with 100 ug/mL ALLN (N-Acetyl-Leu-Leu-Norleucina...
Image no. 2 for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibody (ABIN531958) Western blot analysis of NFKBIA. Using NFKBIA monoclonal antibody, clone 6A920 at 2 ...
Product cited in: Nishioka, Ikezoe, Jing, Umezawa, Yokoyama et al.: "DHMEQ, a novel nuclear factor-kappaB inhibitor, induces selective depletion of alloreactive or phytohaemagglutinin-stimulated peripheral blood mononuclear cells, decreases production of T helper type ..." in: Immunology, Vol. 124, Issue 2, pp. 198-205, 2008 (PubMed).

Endo, Nishio, Enzler, Cottam, Fukuda, James, Karin, Kipps: "BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway." in: Blood, Vol. 109, Issue 2, pp. 703-10, 2007 (PubMed).

Vilimas, Mascarenhas, Palomero, Mandal, Buonamici, Meng, Thompson, Spaulding, Macaroun, Alegre, Kee, Ferrando, Miele, Aifantis: "Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia." in: Nature medicine, Vol. 13, Issue 1, pp. 70-7, 2007 (PubMed).

Strozyk, Pöppelmann, Schwarz, Kulms: "Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome." in: Oncogene, Vol. 25, Issue 47, pp. 6239-51, 2006 (PubMed).

Ishiguro, Ando, Maeda, Hasegawa, Kadomatsu, Ohmiya, Niwa, Xavier, Goto: "Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation." in: Toxicology and applied pharmacology, Vol. 217, Issue 1, pp. 35-42, 2006 (PubMed).

Santhi, Sebastian, Varghese, Prakash, Pillai: "NF-kappaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins." in: Experimental and molecular pathology, Vol. 81, Issue 2, pp. 123-30, 2006 (PubMed).