DNMT3A antibody

Catalog No. ABIN531981

Product Details anti-DNMT3A Antibody

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNMT3A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

Purpose: Mouse monoclonal antibody raised against full length recombinant Dnmt3a.

Cross-Reactivity: Human, Mouse

Immunogen: Recombinant His fusion protein corresponding to full length mouse Dnmt3a.

Clone: 64B1446

Isotype: IgG1

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-DNMT3A antibody (ABIN531981)

Moulin, Cenizo, Antu, André, Pain, Sommer, Debret: "Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts." in: Rejuvenation research, (2016) (PubMed).

Du, Zhou, Liu, Jiang, Wang, Hu, Qi, Zhong, Wang, Li: "Arsenic induces functional re-expression of estrogen receptor ? by demethylation of DNA in estrogen receptor-negative human breast cancer." in: PLoS ONE, Vol. 7, Issue 4, pp. e35957, (2012) (PubMed).

May, Kirchner, Müller, Hartmann, El Hajj, Tresch, Zechner, Mann, Haaf: "Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres." in: Biology of reproduction, Vol. 80, Issue 1, pp. 194-202, (2008) (PubMed).

Xia, Schneider-Stock, Diestel, Habold, Krueger, Roessner, Naumann, Lendeckel: "Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 526-31, (2008) (PubMed).

Hirasawa, Chiba, Kaneda, Tajima, Li, Jaenisch, Sasaki: "Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development." in: Genes & development, Vol. 22, Issue 12, pp. 1607-16, (2008) (PubMed).

Lucifero, La Salle, Bourchis, Martel, Bestor, Trasler: "Coordinate regulation of DNA methyltransferase expression during oogenesis." in: BMC developmental biology, Vol. 7, pp. 36, (2007) (PubMed).

Linhart, Lin, Yamada, Moran, Steine, Gokhale, Lo, Cantu, Ehrich, He, Meissner, Jaenisch: "Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing." in: Genes & development, Vol. 21, Issue 23, pp. 3110-22, (2007) (PubMed).

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: DNMT3A (DNMT3A Products)

Synonyms: DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody

Gene ID: 13435