Kinesin (heavy chain) antibody

Catalog No. ABIN535263

Product Details

Target: Kinesin (heavy chain)

Reactivity: Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against native Kinesin (heavy chain).

Specificity: This antibody recognizes heavy chain of conventional kinesin associated with vesicles and with lower affinity with denaturated molecule. It stains Western blots ofkinesin-enriched preparations. Epitope mapping (by limited proteolysis of partially purified porcine kinesin) followed by immunoblotting has revealed that antibodies MAB3620, MAB3621 and MAB3622 react with differentsets of fragments. This antibody well recognizes kinesin bound to taxol-stabilized microtubules.

Cross-Reactivity: Human, Mouse, Pig, Rat

Immunogen: Native purified porcine Kinesin (heavy chain).

Clone: KN-03

Isotype: IgM

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References

Mac?rek, Dráberová, Richterová, Böhm, Dráber: "Monoclonal antibodies KN-02 and KN-03 against the heavy chain of kinesin." in: Hybridoma and hybridomics, Vol. 21, Issue 6, pp. 457-62, (2003) (PubMed).

Target Details

Target: Kinesin (heavy chain)

Synonyms: KINH antibody, KNS antibody, KNS1 antibody, UKHC antibody, kinesin family member 5B antibody, kinesin family member 5C antibody, KIF5B antibody, Kif5c antibody

Pathways: Peptide Hormone Metabolism