NEFM antibody

Catalog No. ABIN535485

Product Details anti-NEFM Antibody

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEFM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against native Neurofilament medium protein.

Specificity: This antibody reacts with both phosphorylated and non-phosphorylated form of medium neurofilament protein (160 KDa) of various species.

Cross-Reactivity: Mammalian, Pig

Immunogen: Native purified from porcine brain cold stable proteins after depolymerization of microtubules.

Clone: NF-09

Isotype: IgG2a

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

References for anti-NEFM antibody (ABIN535485)

Deng, Li, Liu, Iqbal, Grundke-Iqbal, Brandt, Gong: "Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 1, pp. 138-45, (2008) (PubMed).

Rao, Campbell, Yuan, Kumar, Gotow, Uchiyama, Nixon et al.: "The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport ..." in: The Journal of cell biology, Vol. 163, Issue 5, pp. 1021-31, (2003) (PubMed).

Dráberová, Sulimenko, Kukharskyy, Dráber: "Monoclonal antibody NF-09 specific for neurofilament protein NF-M." in: Folia biologica, Vol. 45, Issue 4, pp. 163-5, (2000) (PubMed).

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: Neurofilament M (160 kD) (NEFM Products)

Synonyms: NEF3 antibody, NF-M antibody, NFM antibody, Nef3 antibody, Nfm antibody, NF160 antibody, NF165 antibody, nef-m antibody, nef3 antibody, nefm antibody, nf-m antibody, zgc:112359 antibody, nefm-a antibody, nefm-b antibody, neurofilament medium antibody, neurofilament triplet M protein antibody, neurofilament, medium polypeptide antibody, neurofilament medium polypeptide antibody, neurofilament medium L homeolog antibody, neurofilament, medium polypeptide a antibody, neurofilament medium S homeolog antibody, NEFM antibody, Nefm antibody, TVAG_582010 antibody, TVAG_379630 antibody, nefm.L antibody, nefma antibody, nefm.S antibody

Pathways: Brown Fat Cell Differentiation