CD36 antibody (PE)

Catalog No. ABIN535990

Product Details anti-CD36 Antibody (PE)

Target: CD36

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD36 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against native CD36.

Specificity: This antibody reacts with CD36 (GPIIIb), a 85 KDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. This antibody TR9 cross-blocks binding of FITC-labeled standard antibody OKM5.
Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells).

Cross-Reactivity: Human

Immunogen: Native purified CD36 from human platelets.

Clone: TR9

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-CD36 antibody (PE) (ABIN535990)

Gaillard, Laugerette, Darcel, El-Yassimi, Passilly-Degrace, Hichami, Khan, Montmayeur, Besnard: "The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1458-68, (2008) (PubMed).

van Oort, van Doorn, Bonen, Glatz, van der Horst, Rodenburg, Luiken: "Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4." in: Biochimica et biophysica acta, Vol. 1781, Issue 1-2, pp. 61-71, (2008) (PubMed).

Won, Bachmann, Kearney: "CD36 is differentially expressed on B cell subsets during development and in responses to antigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 1, pp. 230-7, (2007) (PubMed).

Target Details for CD36

Target: CD36

Alternative Name: CD36 (CD36 Products)

Synonyms: BDPLT10 antibody, CHDS7 antibody, FAT antibody, GP3B antibody, GP4 antibody, GPIV antibody, PASIV antibody, SCARB3 antibody, Fat antibody, Scarb3 antibody, GPIIIB antibody, PAS-4 antibody, zgc:92513 antibody, CD36 molecule antibody, CD36 molecule (thrombospondin receptor) antibody, CD36 antibody, Cd36 antibody, cd36 antibody

Gene ID: 948

Pathways: TLR Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins