XRCC3 antibody

Catalog No. ABIN540236

Product Details anti-XRCC3 Antibody

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of XRCC3.

Specificity: This antibody is specific to XRCC3. This antibody is useful for Western blot, where a band can be seen at 38 kDa. No cross-reactivity was observed with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. The antibody is not applicable for Immunocytochemistry/Immunofluorescence.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to human XRCC3.

Application Details

Application Notes: Immunoprecipitation
Western Blot (1:5000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % sodium azide).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-XRCC3 antibody (ABIN540236)

Compton, Choi, Cesare, Ozgür, Griffith: "Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells." in: Cancer research, Vol. 67, Issue 4, pp. 1513-9, (2007) (PubMed).

Szüts, Simpson, Kabani, Yamazoe, Sale: "Role for RAD18 in homologous recombination in DT40 cells." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 8032-41, (2006) (PubMed).

Nagaraju, Odate, Xie, Scully: "Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 8075-86, (2006) (PubMed).

Yoshihara, Ishida, Kinomura, Katsura, Tsuruga, Tashiro, Asahara, Miyagawa: "XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells." in: The EMBO journal, Vol. 23, Issue 3, pp. 670-80, (2004) (PubMed).

Target Details for XRCC3

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Alternative Name: XRCC3 (XRCC3 Products)

Synonyms: CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody

Gene ID: 7517

Pathways: DNA Damage Repair