OGG1 antibody (AA 1-100)

Catalog No. ABIN540355

Product Details anti-OGG1 Antibody

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Binding Specificity: AA 1-100

Reactivity: Human, Rat, Monkey, Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OGG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of OGG1.

Specificity: This antibody is specific to human Ogg1.

Cross-Reactivity: Human, Monkey, Primate, Rat

Immunogen: A synthetic peptide corresponding to amino acids 1-100 of human OGG1.

Application Details

Application Notes: Western Blot (1:500-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000)
Immunohistochemistry (Frozen sections) (1:25-1:100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-OGG1 antibody (ABIN540355)

Xydas, Kherani, Chang, Klotz, Hay, Mutrie, Moss, Gu, Schulman, Gao, Hu, Wu, Wei, Oz, Wang: "beta(2)-Adrenergic stimulation attenuates left ventricular remodeling, decreases apoptosis, and improves calcium homeostasis in a rodent model of ischemic cardiomyopathy." in: The Journal of pharmacology and experimental therapeutics, Vol. 317, Issue 2, pp. 553-61, (2006) (PubMed).

Rachek, Thornley, Grishko, LeDoux, Wilson: "Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria." in: Diabetes, Vol. 55, Issue 4, pp. 1022-8, (2006) (PubMed).

Chen, Yu, Zhu, Lopez: "The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells." in: Cancer research, Vol. 66, Issue 7, pp. 3485-94, (2006) (PubMed).

Roseborough, Gao, Chen, Trush, Zhou, Williams, Wei: "The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cord." in: The American journal of pathology, Vol. 168, Issue 5, pp. 1443-51, (2006) (PubMed).

Target Details for OGG1

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Alternative Name: OGG1 (OGG1 Products)

Synonyms: OGG1 antibody, zgc:158858 antibody, 8-oxoguanine-DNA glycosylase 1 antibody, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 antibody, ATOGG1 antibody, F8K7.14 antibody, F8K7_14 antibody, 19.m02329 antibody, DDBDRAFT_0184479 antibody, DDBDRAFT_0233024 antibody, DDB_0184479 antibody, DDB_0233024 antibody, ogg1 antibody, Tb04.1H19.930 antibody, HMMH antibody, HOGG1 antibody, MUTM antibody, OGH1 antibody, Mmh antibody, 8-oxoguanine DNA glycosylase antibody, 8-oxoguanine DNA glycosylase L homeolog antibody, 8-oxoguanine-DNA glycosylase 1 antibody, 8-OXOGUANINE DNA GLYCOSYLASE antibody, putative 8-oxoguanine DNA glycosylase antibody, 8-oxoguanine DNA-glycosylase antibody, N-glycosylase/DNA lyase OGG1 antibody, 8-oxoguanine DNA-glycosylase 1 antibody, OGG1 antibody, ogg1.L antibody, ogg1 antibody, ECU08_0770 antibody, CA_C2707 antibody, BBOV_I004290 antibody, Smp_074010.1 antibody, LOC9329243 antibody, Tb927.4.2480 antibody, Ogg1 antibody

Gene ID: 4968

Pathways: DNA Damage Repair