NPC1L1 antibody (AA 500-600)

Catalog No. ABIN540362

Product Details anti-NPC1L1 Antibody

Target: NPC1L1 (NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))

Binding Specificity: AA 500-600

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPC1L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Npc1l1.

Specificity: This antibody is specific to NPC1L1 protein.

Cross-Reactivity: Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to amino acids 500-600 of rat Npc1l1.

Application Details

Application Notes: Immunohistochemistry (1 μg/mL)
Western Blot (1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:250)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-citrate/phosphate buffer, pH 7.0-8.0

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-NPC1L1 antibody (ABIN540362)

Montoudis, Seidman, Boudreau, Beaulieu, Menard, Elchebly, Mailhot, Sane, Lambert, Delvin, Levy: "Intestinal fatty acid binding protein regulates mitochondrion beta-oxidation and cholesterol uptake." in: Journal of lipid research, Vol. 49, Issue 5, pp. 961-72, (2008) (PubMed).

Kaufmann, Krise: "Niemann-Pick C1 functions in regulating lysosomal amine content." in: The Journal of biological chemistry, Vol. 283, Issue 36, pp. 24584-93, (2008) (PubMed).

Altmann, Davis, Zhu, Yao, Hoos, Tetzloff, Iyer, Maguire, Golovko, Zeng, Wang, Murgolo, Graziano: "Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption." in: Science (New York, N.Y.), Vol. 303, Issue 5661, pp. 1201-4, (2004) (PubMed).

Target Details for NPC1L1

Target: NPC1L1 (NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))

Alternative Name: Npc1l1 (NPC1L1 Products)

Synonyms: NPC1L1 antibody, 9130221N23Rik antibody, Gm243 antibody, NPC11L1 antibody, NPC1 like intracellular cholesterol transporter 1 antibody, NPC1 like 1 antibody, NPC1-like 1 antibody, NPC1L1 antibody, npc1l1 antibody, Npc1l1 antibody

Gene ID: 432367