LOX antibody (AA 78-115)

Catalog No. ABIN540432

Product Details anti-LOX Antibody

Target: LOX (Lysyl Oxidase (LOX))

Binding Specificity: AA 78-115

Reactivity: Human, Mouse, Rat, Pig, Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Lox.

Specificity: This antibody recognizes the pro-enzyme (50 KDa) and pro-peptide. The pro-peptide runs at ~18-20 KDa when not glycosylated and ~35 KDa on SDS-PAGE when N-glycosylated.

Cross-Reactivity: Human, Mouse, Pig, Primate, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to amino acids 78-115 of mouse Lox.

Isotype: IgG

Application Details

Application Notes: Immunocytochemistry (1:50)
Immunofluorescence (1:50)
Immunohistochemistry (0.5-1 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:250)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-LOX antibody (ABIN540432)

Guo, Pischon, Palamakumbura, Trackman: "Intracellular distribution of the lysyl oxidase propeptide in osteoblastic cells." in: American journal of physiology. Cell physiology, Vol. 292, Issue 6, pp. C2095-102, (2007) (PubMed).

Hong, Pischon, Santana, Palamakumbura, Chase, Gantz, Guo, Uzel, Ma, Trackman: "A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures." in: Journal of cellular physiology, Vol. 200, Issue 1, pp. 53-62, (2004) (PubMed).

Palamakumbura, Jeay, Guo, Pischon, Sommer, Sonenshein, Trackman: "The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40593-600, (2004) (PubMed).

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: Lysyl oxidase (LOX Products)

Synonyms: LOX antibody, Xlox antibody, MGC146507 antibody, lox antibody, zgc:77447 antibody, AI893619 antibody, TSC-160 antibody, H-rev142 antibody, Rrg1 antibody, lysyl oxidase antibody, lysyl oxidase a antibody, lysyl oxidase L homeolog antibody, LOX antibody, lox antibody, loxa antibody, lox.L antibody, Lox antibody

Pathways: SARS-CoV-2 Protein Interactome