TBK1 antibody (C-Term)

Catalog No. ABIN541168

Product Details anti-TBK1 Antibody

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of TBK1.

Specificity: A 84 KDa band should be detected. It is human, mouse and rat reactive and has no cross response to IKKa, IKKb, IKKy, or IKKe.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide corresponding to C-terminus 17 amino acids of human TBK1.

Application Details

Application Notes: Western Blot (0.5-1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TBK1 antibody (ABIN541168)

Pomerantz, Baltimore: "NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase." in: The EMBO journal, Vol. 18, Issue 23, pp. 6694-704, (2000) (PubMed).

Tojima, Fujimoto, Delhase, Chen, Hatakeyama, Nakayama, Kaneko, Nimura, Motoyama, Ikeda, Karin, Nakanishi: "NAK is an IkappaB kinase-activating kinase." in: Nature, Vol. 404, Issue 6779, pp. 778-82, (2000) (PubMed).

Bonnard, Mirtsos, Suzuki, Graham, Huang, Ng, Itié, Wakeham, Shahinian, Henzel, Elia, Shillinglaw, Mak, Cao, Yeh: "Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription." in: The EMBO journal, Vol. 19, Issue 18, pp. 4976-85, (2000) (PubMed).

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1 (TBK1 Products)

Synonyms: nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody

Gene ID: 29110

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome