CARD9 antibody (AA 521-536)

Catalog No. ABIN541183

Product Details anti-CARD9 Antibody

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Binding Specificity: AA 521-536

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD9 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CARD9.

Sequence: DRENTTGSDN TDTEGS

Specificity: The sequence is different from that of rat origin by two amino acids. A band at approximately 59 KDa can be detected.

Cross-Reactivity: Human

Immunogen: A synthetic peptide corresponding to amino acids 521-536 of human CARD9.

Application Details

Application Notes: Western Blot (0.5-1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CARD9 antibody (ABIN541183)

Gavino, Hamel, Zeng, Legault, Guiot, Chankowsky, Lejtenyi, Lemire, Alarie, Dufresne, Boursiquot, McIntosh, Langelier, Behr, Sheppard, Foulkes, Vinh: "Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians." in: The Journal of allergy and clinical immunology, Vol. 137, Issue 4, pp. 1178-1188.e7, (2016) (PubMed).

Bertin, Guo, Wang, Srinivasula, Jacobson, Poyet, Merriam, Du, Dyer, Robison, DiStefano, Alnemri: "CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41082-6, (2001) (PubMed).

Target Details for CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Alternative Name: CARD9 (CARD9 Products)

Synonyms: Gm782 antibody, card9 antibody, CANDF2 antibody, hCARD9 antibody, caspase recruitment domain family, member 9 antibody, caspase recruitment domain family member 9 antibody, Card9 antibody, CARD9 antibody, card9 antibody

Gene ID: 64170

Pathways: Activation of Innate immune Response