CARD8 antibody (C-Term)

Catalog No. ABIN541215

Product Details anti-CARD8 Antibody

Target: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD8 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CARD8.

Specificity: An approximate 45 KDa can be detected.

Cross-Reactivity: Human

Immunogen: A synthetic peptide corresponding to C-terminus of human CARD8.

Application Details

Application Notes: Western Blot (2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CARD8 antibody (ABIN541215)

Razmara, Srinivasula, Wang, Poyet, Geddes, DiStefano, Bertin, Alnemri: "CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13952-8, (2002) (PubMed).

Pathan, Marusawa, Krajewska, Matsuzawa, Kim, Okada, Torii, Kitada, Krajewski, Welsh, Pio, Godzik, Reed: "TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer." in: The Journal of biological chemistry, Vol. 276, Issue 34, pp. 32220-9, (2001) (PubMed).

Scholl, McLoughlin, Ehler, de Giovanni, Schäfer: "DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis." in: The Journal of cell biology, Vol. 151, Issue 3, pp. 495-506, (2000) (PubMed).

Target Details for CARD8

Target: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Alternative Name: CARD8 / NDPP1 (CARD8 Products)

Synonyms: CARD8 antibody, CARDINAL antibody, DACAR antibody, DAKAR antibody, NDPP antibody, NDPP1 antibody, TUCAN antibody, caspase recruitment domain family, member 8 antibody, caspase recruitment domain-containing protein 8 antibody, caspase recruitment domain family member 8 antibody, CARD8 antibody, LOC718594 antibody

Gene ID: 22900

Pathways: Positive Regulation of Endopeptidase Activity