PARL
Reactivity: Human, Mouse, Rat, Dog
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western Blot (1-2 μg/mL) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.02 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Chao, Parganas, Boyd, Hong, Opferman, Ihle: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).
Cipolat, Rudka, Hartmann, Costa, Serneels, Craessaerts, Metzger, Frezza, Annaert, DAdamio, Derks, Dejaegere, Pellegrini, DHooge, Scorrano, De Strooper: "Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling." in: Cell, Vol. 126, Issue 1, pp. 163-75, (2006) (PubMed).
Pellegrini, Passer, Canelles, Lefterov, Ganjei, Fowlkes, Koonin, DAdamio: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).