DYRK1A
Reactivity: Human, Rat, Rabbit
WB, IHC, IF, IC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Chang, Lin, Yang, Yen, Lai, Chen, Liang, Yu: "Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 11, pp. 2377-85, (2007) (PubMed).
Alvarez, Altafaj, Aranda, de la Luna: "DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding." in: Molecular biology of the cell, Vol. 18, Issue 4, pp. 1167-78, (2007) (PubMed).
Adayev, Chen-Hwang, Murakami, Lee, Bolton, Hwang: "Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro." in: Biochemistry, Vol. 46, Issue 25, pp. 7614-24, (2007) (PubMed).