AKR1A1 antibody (C-Term)

Catalog No. ABIN543542

Product Details anti-AKR1A1 Antibody

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of AKR1A1.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human AKR1A1.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-AKR1A1 antibody (ABIN543542)

Quiñones-Lombraña, Ferguson, Hageman Blair, Kalabus, Redzematovic, Blanco: "Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome." in: Pharmaceutical research, Vol. 31, Issue 7, pp. 1644-55, (2014) (PubMed).

Steuber, Heine, Podjarny, Klebe: "Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features." in: Journal of molecular biology, Vol. 379, Issue 5, pp. 991-1016, (2008) (PubMed).

Bohren, Brownlee, Milne, Gabbay, Harrison: "The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism." in: Biochimica et biophysica acta, Vol. 1748, Issue 2, pp. 201-12, (2005) (PubMed).

El-Kabbani, Green, Lin, Carson, Narayana, Moore, Flynn, DeLucas: "Structures of human and porcine aldehyde reductase: an enzyme implicated in diabetic complications." in: Acta crystallographica. Section D, Biological crystallography, Vol. 50, Issue Pt 6, pp. 859-68, (2004) (PubMed).

Target Details for AKR1A1

Target: AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))

Alternative Name: AKR1A1 / ALDR1 (AKR1A1 Products)

Synonyms: akr1a1 antibody, zgc:100940 antibody, aldr1 antibody, alr antibody, arm antibody, dd3 antibody, AKR1A1 antibody, zgc:110225 antibody, ALDR1 antibody, ALR antibody, ARM antibody, DD3 antibody, Akr1a4 antibody, 2610201A18Rik antibody, ALR1 antibody, Alr antibody, aldo-keto reductase family 1, member A1a (aldehyde reductase) antibody, aldo-keto reductase family 1, member A1 (aldehyde reductase) antibody, aldo-keto reductase family 1 member A1 antibody, aldo-keto reductase family 1, member A1b (aldehyde reductase) antibody, aldehyde reductase antibody, aldo-keto reductase family 1, member A1 (aldehyde reductase) L homeolog antibody, akr1a1a antibody, akr1a1 antibody, AKR1A1 antibody, akr1a1b antibody, Akr1a1 antibody, akr1a1.L antibody

Gene ID: 10327

Pathways: Monocarboxylic Acid Catabolic Process