ACVR1C/ALK7 antibody (N-Term)

Catalog No. ABIN543603

Product Details anti-ACVR1C/ALK7 Antibody

Target: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR1C/ALK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of ACVR1C.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ACVR1C.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-ACVR1C/ALK7 antibody (ABIN543603)

Kim, van Gelder, Kim, Lee, Baik, Chun, Lee, Choi, Kim: "Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28458-65, (2004) (PubMed).

Munir, Xu, Wu, Yang, Lala, Peng: "Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31277-86, (2004) (PubMed).

Roberts, Hu, Qiu, Leung, Caniggia, Gruslin, Tsang, Peng: "Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta." in: Biology of reproduction, Vol. 68, Issue 5, pp. 1719-26, (2003) (PubMed).

Target Details for ACVR1C/ALK7

Target: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Abstract: ACVR1C Products

Synonyms: ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody

Gene ID: 130399

Pathways: Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity