RAGE antibody (N-Term)

Catalog No. ABIN545221

Product Details anti-RAGE Antibody

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAGE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of AGER.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human AGER.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-RAGE antibody (ABIN545221)

Kuniyasu, Chihara, Takahashi: "Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer." in: Oncology reports, Vol. 10, Issue 2, pp. 445-8, (2003) (PubMed).

Shanmugam, Kim, Lanting, Natarajan: "Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products." in: The Journal of biological chemistry, Vol. 278, Issue 37, pp. 34834-44, (2003) (PubMed).

Schlueter, Hauke, Flohr, Rogalla, Bullerdiek: "Tissue-specific expression patterns of the RAGE receptor and its soluble forms--a result of regulated alternative splicing?" in: Biochimica et biophysica acta, Vol. 1630, Issue 1, pp. 1-6, (2003) (PubMed).

Target Details for RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Alternative Name: RAGE / AGER (AGER Products)

Synonyms: RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody

Gene ID: 177

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins