PKLR antibody (N-Term)

Catalog No. ABIN545496

Product Details anti-PKLR Antibody

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKLR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PKLR.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PKLR.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PKLR antibody (ABIN545496)

Wang, Chu, Das, Ren, Hasstedt, Elbein: "Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians." in: Diabetes, Vol. 51, Issue 9, pp. 2861-5, (2002) (PubMed).

Valentini, Chiarelli, Fortin, Dolzan, Galizzi, Abraham, Wang, Bianchi, Zanella, Mattevi: "Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23807-14, (2002) (PubMed).

Mateu, Pérez-Lezaun, Martínez-Arias, Andrés, Vallés, Bertranpetit, Calafell: "PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations." in: Human genetics, Vol. 110, Issue 6, pp. 532-44, (2002) (PubMed).

Target Details for PKLR

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Alternative Name: PKLR (PKLR Products)

Synonyms: PK1 antibody, PKL antibody, PKR antibody, PKRL antibody, RPK antibody, Pklg antibody, wu:fd15e01 antibody, wu:fi37e08 antibody, pk1 antibody, PKLR antibody, Pk-1 antibody, Pk1 antibody, R-PK antibody, pklr antibody, pyruvate kinase L/R antibody, pyruvate kinase, liver and RBC antibody, pyruvate kinase, liver and RBC L homeolog antibody, pyruvate kinase liver and red blood cell antibody, pyruvate kinase PKLR-like antibody, PKLR antibody, Pklr antibody, pklr antibody, pklr.L antibody, LOC100621940 antibody

Gene ID: 5313

Pathways: Ribonucleoside Biosynthetic Process