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PKLR antibody

PKLR Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259945
  • Target See all PKLR Antibodies
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    Reactivity
    • 67
    • 31
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 67
    • 7
    Rabbit
    Clonality
    • 69
    • 5
    Polyclonal
    Conjugate
    • 33
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKLR antibody is un-conjugated
    Application
    • 49
    • 41
    • 35
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PKLR (NP_000289.1).
    Isotype
    IgG
    Top Product
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  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    Alternative Name
    PKLR (PKLR Products)
    Synonyms
    PK1 antibody, PKL antibody, PKR antibody, PKRL antibody, RPK antibody, Pklg antibody, wu:fd15e01 antibody, wu:fi37e08 antibody, pk1 antibody, PKLR antibody, Pk-1 antibody, Pk1 antibody, R-PK antibody, pklr antibody, pyruvate kinase L/R antibody, pyruvate kinase, liver and RBC antibody, pyruvate kinase, liver and RBC L homeolog antibody, pyruvate kinase liver and red blood cell antibody, pyruvate kinase PKLR-like antibody, PKLR antibody, Pklr antibody, pklr antibody, pklr.L antibody, LOC100621940 antibody
    Background
    The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
    Gene ID
    5313
    UniProt
    P30613
    Pathways
    Ribonucleoside Biosynthetic Process
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