TAB1 antibody (C-Term)

Catalog No. ABIN548637

Product Details anti-TAB1 Antibody

Target: TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAB1 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP3K7IP1.

Cross-Reactivity: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to C-terminus residues surrounding S423 of human MAP3K7IP1.

Application Details

Application Notes: ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TAB1 antibody (ABIN548637)

Zhou, Zheng, Chen, Xie, Kolatkar, Zarubin, Ye, Akella, Lin, Goldsmith, Han: "Determinants that control the specific interactions between TAB1 and p38alpha." in: Molecular and cellular biology, Vol. 26, Issue 10, pp. 3824-34, (2006) (PubMed).

Conner, Kular, Peggie, Shepherd, Schüttelkopf, Cohen, Van Aalten: "TAK1-binding protein 1 is a pseudophosphatase." in: The Biochemical journal, Vol. 399, Issue 3, pp. 427-34, (2006) (PubMed).

Singhirunnusorn, Suzuki, Kawasaki, Saiki, Sakurai et al.: "Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex ..." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 7359-68, (2005) (PubMed).

Target Details for TAB1

Target: TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))

Alternative Name: TAB1 / MAP3K7IP1 (TAB1 Products)

Synonyms: 3'-Tab1 antibody, MAP3K7IP1 antibody, 2310012M03Rik antibody, Map3k7ip1 antibody, b2b449Clo antibody, TGF-beta activated kinase 1 (MAP3K7) binding protein 1 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 1 antibody, TAB1 antibody, Tab1 antibody

Gene ID: 10454

Pathways: TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades