ATP1A3 antibody (Middle Region)

Catalog No. ABIN5514515

Product Details anti-ATP1A3 Antibody

Target: ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVAEIPFNST NKYQLSIHET EDPNDNRYLL VMKGAPERIL DRCSTILLQG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against AT1A3. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-ATP1A3 antibody is: synthetic peptide directed towards the middle region of Human AT1A3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP1A3

Target: ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))

Alternative Name: ATP1A3 (ATP1A3 Products)

Synonyms: AHC2 antibody, DYT12 antibody, RDP antibody, Atpa-2 antibody, Atpa1a3 antibody, ATPa1a3 antibody, atp[a]3A antibody, cb706 antibody, fj35g11 antibody, wu:fj35g11 antibody, wu:fq14g09 antibody, atp[a]3B antibody, cb705 antibody, wu:fj56a06 antibody, ATPase Na+/K+ transporting subunit alpha 3 antibody, ATPase, Na+/K+ transporting, alpha 3 polypeptide antibody, ATPase, Na+/K+ transporting, alpha 3 polypeptide L homeolog antibody, ATPase, Na+/K+ transporting, alpha 3b polypeptide antibody, ATPase, Na+/K+ transporting, alpha 3a polypeptide antibody, ATP1A3 antibody, Atp1a3 antibody, atp1a3.L antibody, atp1a3b antibody, atp1a3a antibody

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RDP, AHC2, CAPOS, DYT12,

Protein Interaction Partner: UBC, LGR4, CLN5, ATXN1,

Protein Size: 1013

Gene ID: 478

NCBI Accession: NP_689509

UniProt: P13637

Pathways: Thyroid Hormone Synthesis, Proton Transport, Ribonucleoside Biosynthetic Process