AIM2 antibody (C-Term)

Catalog No. ABIN5514522

This Rabbit Polyclonal antibody specifically detects AIM2 in WB. It exhibits reactivity toward Human and Horse.

Quick Overview for AIM2 antibody (C-Term) (ABIN5514522)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AIM2 Antibody

Binding Specificity: C-Term

Purpose: AIM2 Antibody - C-terminal region

Sequence: TGKMEVLGVR NEDTMKCKEG DKVRLTFFTL SKNGEKLQLT SGVHSTIKVI

Predicted Reactivity: Horse: 83%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AIM2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AIM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50506-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background:

Background Information: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.

Gene Name: absent in melanoma 2

Alternative Symbols: PYHIN4

Protein Name: Interferon-inducible protein AIM2

Molecular Weight: 37kDa

Gene ID: 9447

NCBI Accession: NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome