AIM2 antibody (C-Term)

Catalog No. ABIN5514522

This Rabbit Polyclonal antibody specifically detects AIM2 in WB. It exhibits reactivity toward Human and Horse.

Quick Overview for AIM2 antibody (C-Term) (ABIN5514522)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AIM2 Antibody

Binding Specificity: C-Term

Sequence: TGKMEVLGVR NEDTMKCKEG DKVRLTFFTL SKNGEKLQLT SGVHSTIKVI

Predicted Reactivity: Horse: 83%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AIM2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AIM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.

Alias Symbols: AIM2,

Protein Interaction Partner: APPBP2,

Protein Size: 343

Gene ID: 9447

NCBI Accession: NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome