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CREM antibody (C-Term)
CREM
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CREM Antibody
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Target
See all CREM Antibodies
CREM
(CAMP Responsive Element Modulator (CREM))
Binding Specificity
All epitopes for CREM antibodies
C-Term
Reactivity
All reactivities for CREM antibodies
Human
Host
All hosts for CREM antibodies
Rabbit
Clonality
All clonalities for CREM antibodies
Polyclonal
Conjugate
All conjugates for CREM antibodies
This CREM antibody is un-conjugated
Application
All applications for CREM antibodies
Western Blotting (WB)
Sequence
LHSPQQLAEE ATRKRELRLM KNREAAKECR RRKKEYVKCL ESRVAVLEVQ
Characteristics
This is a rabbit polyclonal antibody against CREM. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CREM
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CREM
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Target
CREM
(CAMP Responsive Element Modulator (CREM))
Alternative Name
CREM (CREM Products )
Synonyms
CREM antibody, ICER antibody, CREM-2 antibody, hCREM-2 antibody, ICERI antibody, Icer antibody, cAMP responsive element modulator antibody, CREM antibody, Crem antibody
Background
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. Alias Symbols: CREM, Protein Interaction Partner: CREB1, PIAS3, CASP8AP2, UBE2I, UBC, SP100, ATXN1, EMP3, HHV8GK18_gp81, MAPK3, CREB3L4, HDAC1, CREB3L1, TAF4, CAMK2D, GSK3A, FHL5, GSK3B, KCNIP3, CAMK2G, PRKACA, CSNK1A1, CREBBP, TBP, PRKCA, SPI1, CREM, ATF1, CDC34, CDK1, CSNK2A2, CSNK2A1, CD34, Protein Size: 221
Gene ID
1390
Pathways
Retinoic Acid Receptor Signaling Pathway
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