CYB5R3 antibody (Middle Region)

Catalog No. ABIN5514664

Product Details anti-CYB5R3 Antibody

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYB5R3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FRGPSGLLVY QGKGKFAIRP DKKSNPIIRT VKSVGMIAGG TGITPMLQVI

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYB5R3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYB5R3

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Alternative Name: CYB5R3 (CYB5R3 Products)

Synonyms: B5R antibody, DIA1 antibody, Dia1 antibody, Nadhcb5 antibody, RNNADHCB5 antibody, 0610016L08Rik antibody, 2500002N19Rik antibody, C85115 antibody, Dia-1 antibody, WU:AL591952.1-001 antibody, WU:AL591952.1-002 antibody, WU:AL591952.1-003 antibody, WU:Cyb5r3 antibody, fc32h03 antibody, zgc:77071 antibody, wu:fc32h03 antibody, dia1 antibody, CB5R antibody, DDBDRAFT_0218707 antibody, DDBDRAFT_0266821 antibody, DDB_0218707 antibody, DDB_0266821 antibody, cytochrome b5 reductase 3 antibody, cytochrome b5 reductase 3 L homeolog antibody, NADH-cytochrome b5 reductase antibody, CYB5R3 antibody, Cyb5r3 antibody, cyb5r3 antibody, cyb5r3.L antibody, CNM00240 antibody, Tb11.47.0018 antibody, cyb5r1 antibody

Background: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

Alias Symbols: B5R, DIA1

Protein Size: 334

Gene ID: 1727

NCBI Accession: NM_000398, NP_000389

Pathways: SARS-CoV-2 Protein Interactome