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DGCR8 antibody (Middle Region)
DGCR8
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DGCR8 Antibody
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Target
See all DGCR8 Antibodies
DGCR8
(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
Binding Specificity
All epitopes for DGCR8 antibodies
Middle Region
Reactivity
All reactivities for DGCR8 antibodies
Human
Host
All hosts for DGCR8 antibodies
Rabbit
Clonality
All clonalities for DGCR8 antibodies
Polyclonal
Conjugate
All conjugates for DGCR8 antibodies
This DGCR8 antibody is un-conjugated
Application
All applications for DGCR8 antibodies
Western Blotting (WB)
Sequence
TEEKYGGDSD HPSDGETSVQ PMMTKIKTVL KSRGRPPTEP LPDGWIMTFH
Characteristics
This is a rabbit polyclonal antibody against DGCR8. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human DGCR8
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for DGCR8
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Target
DGCR8
(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
Alternative Name
DGCR8 (DGCR8 Products )
Synonyms
MGC78846 antibody, DGCR8 antibody, gy1 antibody, dgcrk6 antibody, C22orf12 antibody, DGCRK6 antibody, Gy1 antibody, pasha antibody, D16H22S1742E antibody, D16H22S788E antibody, D16Wis2 antibody, N41 antibody, Vo59c07 antibody, si:ch211-106a19.4 antibody, wu:fc23f08 antibody, wu:fc38f06 antibody, DGCR8 microprocessor complex subunit L homeolog antibody, DiGeorge syndrome critical region gene 8 antibody, DGCR8 microprocessor complex subunit antibody, DGCR8, microprocessor complex subunit antibody, microRNA 3618 antibody, dgcr8.L antibody, DGCR8 antibody, dgcr8 antibody, Dgcr8 antibody, MIR3618 antibody
Background
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. Alias Symbols: DGCR8, C22orf12, DGCRK6, LP4941, Protein Interaction Partner: MEOX2, PYCRL, DROSHA, RAE1, MAPK1, PRMT1, ERH, CDKN2A, BMI1, SRPK2, SRPK1, CDT1, NAT10, PLEK2, RPRD2, MAPRE2, PRPF4, FLII, APP, CUL3, DDX17, HNRNPR, NCL, ILF3, HSPA8, HSPA5, HNRNPU, HNRNPH1, FUS, DHX9, DDX5, Protein Size: 773
Gene ID
54487
NCBI Accession
NP_073557
UniProt
Q8WYQ5
Pathways
Regulatory RNA Pathways
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