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EIF3F antibody (Middle Region)
EIF3F
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EIF3F Antibody
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Target
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EIF3F
(Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))
Binding Specificity
All epitopes for EIF3F antibodies
Middle Region
Reactivity
All reactivities for EIF3F antibodies
Human
Host
All hosts for EIF3F antibodies
Rabbit
Clonality
All clonalities for EIF3F antibodies
Polyclonal
Conjugate
All conjugates for EIF3F antibodies
This EIF3F antibody is un-conjugated
Application
All applications for EIF3F antibodies
Western Blotting (WB)
Sequence
VPHNESEDEV AVDMEFAKNM YELHKKVSPN ELILGWYATG HDITEHSVLI
Characteristics
This is a rabbit polyclonal antibody against EIF3F. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human EIF3F
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for EIF3F
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Target
EIF3F
(Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))
Alternative Name
EIF3F (EIF3F Products )
Synonyms
AO090005001590 antibody, Dmel\CG9769 antibody, eIF3-S5 antibody, eif3f antibody, LOC733116 antibody, eIF3f antibody, EIF3S5 antibody, eIF3-p47 antibody, 0610037M02Rik antibody, AA409853 antibody, Eif3s5 antibody, eukaryotic translation initiation factor 3 subunit F antibody, hypothetical protein antibody, CG9769 gene product from transcript CG9769-RA antibody, eukaryotic translation initiation factor 3 subunit 5 antibody, eukaryotic translation initiation factor 3, subunit F antibody, Eukaryotic translation initiation factor 3 subunit F antibody, eif3f antibody, ANI_1_120074 antibody, AOR_1_2780174 antibody, PTRG_03897 antibody, PAAG_00376 antibody, MCYG_08502 antibody, MGYG_08653 antibody, PGTG_04587 antibody, CG9769 antibody, LOC733116 antibody, EIF3F antibody, Eif3f antibody, eif-3.F antibody
Background
EIF3F is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Alias Symbols: EIF3F {ECO:0000255|HAMAP-Rule:MF_03005 Protein Interaction Partner: HUWE1, UBC, SUMO2, RNF2, FBXO6, RPS6KB1, IGSF8, ICAM1, CD81, DDX3X, gag-pol, EIF3D, EIF3B, ATXN1, SMAD9, FN1, EIF3M, EIF3C, EIF3A, MSMO1, EIF3E, ATP6V1A, APP, EIF3L, EIF3K, MRPL46, EIF3I, EIF3H, EIF3G, UBD, HNRNPK, CDK11B, YWHAZ, NOTCH1, DTX1, RAD21, FBXO Protein Size: 357
Gene ID
8665
NCBI Accession
NP_003745
UniProt
O00303
Pathways
Ribonucleoprotein Complex Subunit Organization
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