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HTRA2 antibody (Middle Region)
HTRA2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HTRA2 Antibody
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Target
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HTRA2
(HtrA Serine Peptidase 2 (HTRA2))
Binding Specificity
All epitopes for HTRA2 antibodies
Middle Region
Reactivity
All reactivities for HTRA2 antibodies
Human
Host
All hosts for HTRA2 antibodies
Rabbit
Clonality
All clonalities for HTRA2 antibodies
Polyclonal
Conjugate
All conjugates for HTRA2 antibodies
This HTRA2 antibody is un-conjugated
Application
All applications for HTRA2 antibodies
Western Blotting (WB)
Sequence
TMKVTAGISF AIPSDRLREF LHRGEKKNSS SGISGSQRRY IGVMMLTLSP
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HTRA2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for HTRA2
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Target
HTRA2
(HtrA Serine Peptidase 2 (HTRA2))
Alternative Name
HTRA2 (HTRA2 Products )
Synonyms
CG8464 antibody, DmHtrA2 antibody, Dmel\\CG8464 antibody, HtrA2/Omi antibody, Omi antibody, dOmi antibody, domi antibody, htrA2 antibody, omi antibody, HTRA2 antibody, PRSS25 antibody, OMI antibody, PARK13 antibody, AI481710 antibody, Prss25 antibody, mnd2 antibody, HTRA2-related serine protease antibody, HtrA serine peptidase 2 antibody, HtrA2 antibody, HTRA2 antibody, htra2 antibody, Htra2 antibody
Background
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. Alias Symbols: OMI, PARK13, PRSS25 Protein Size: 361
Gene ID
27429
NCBI Accession
NM_013247 , NP_037379
Pathways
Positive Regulation of Endopeptidase Activity
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