IL1RAP antibody (C-Term)

Catalog No. ABIN5514899

Product Details anti-IL1RAP Antibody

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RAP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVQYKAVKET KVKELKRAKT VLTVIKWKGE KSKYPQGRFW KQLQVAMPVK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IL1RAP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL1RAP

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Alternative Name: IL1RAP (IL1RAP Products)

Synonyms: IL1RAP antibody, il-1racp antibody, il-racp antibody, il1r3 antibody, C3orf13 antibody, IL-1RAcP antibody, IL1R3 antibody, 6430709H04Rik antibody, AI255955 antibody, AV239853 antibody, IL-1RAcp antibody, Il1racpb antibody, interleukin 1 receptor accessory protein antibody, IL1RAP antibody, il1rap antibody, il-1racp antibody, Il1rap antibody

Background: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Alias Symbols: IL1R3, C3orf13, IL-1RAcP

Protein Size: 570

Gene ID: 3556

NCBI Accession: NM_001167928, NP_001161400

UniProt: Q9NPH3

Pathways: NF-kappaB Signaling, Growth Factor Binding