IL-11 antibody (N-Term)

Catalog No. ABIN5514900

Product Details anti-IL-11 Antibody

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RLVLVVLSLW PDTAVAPGPP PGPPRVSPDP RAELDSTVLL TRSLLADTRQ

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Alternative Name: IL11 (IL11 Products)

Synonyms: IL11 antibody, AGIF antibody, IL-11 antibody, Il-11 antibody, interleukin 11 antibody, IL11 antibody, Il11 antibody

Background: The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alias Symbols: AGIF, IL-11

Protein Size: 199

Gene ID: 3589

NCBI Accession: NM_000641, NP_000632

UniProt: P20809

Pathways: JAK-STAT Signaling, Negative Regulation of Hormone Secretion