LIM Domain Binding 1 Protein antibody (C-Term)

Catalog No. ABIN5514920

Product Details anti-LIM Domain Binding 1 Protein Antibody

Target: LIM Domain Binding 1 Protein (LDB1) (LIM Domain Binding 1 (LDB1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Binding 1 Protein antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VAPPAEPTRQ QPSKRRKRKM SGGSTMSSGG GNTNNSNSKK KSPASTFALS

Characteristics: This is a rabbit polyclonal antibody against LDB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIM Domain Binding 1 Protein

Target: LIM Domain Binding 1 Protein (LDB1) (LIM Domain Binding 1 (LDB1))

Alternative Name: LDB1 (LDB1 Products)

Synonyms: CLIM2 antibody, NLI antibody, chi antibody, clim2 antibody, nli antibody, xldb1 antibody, ldb1 antibody, LDB1 antibody, ldb4 antibody, ldb4b antibody, LIM domain binding 1 antibody, LIM domain binding 1 L homeolog antibody, LIM-domain binding 1b antibody, LIM domain binding protein 1 antibody, LIM domain binding 1a antibody, Ldb1 antibody, LDB1 antibody, ldb1.L antibody, ldb1b antibody, xldb1 antibody, ldb1a antibody

Background: LDB1 binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. It may regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. It plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. It acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. It acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.

Alias Symbols: LDB1, CLIM2,

Protein Interaction Partner: LHX8, LHX6, SSBP3, LMO4, LMX1B, LMO2, LMO1, POLR1B, LSM7, IRAK3, UBC, PSMD10, PSMA1, TRIM33, ATXN1, RNF38, RNF6, rlim-a, RLIM, RB1, TAL1, LHX2, LMO3, SSBP4, SSBP2, TOLLIP, CTDSP1, LHX3, SSBP1, ISL1, LMX1A, ESR1, TCF3, SP1, CBFA2T3,

Protein Size: 411

Gene ID: 8861

UniProt: Q86U70

Pathways: Stem Cell Maintenance, Chromatin Binding