NADPH Oxidase 4 antibody (C-Term)
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- Target See all NADPH Oxidase 4 (NOX4) Antibodies
- NADPH Oxidase 4 (NOX4)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NADPH Oxidase 4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LLFDEIAKYN RGKTVGVFCC GPNSLSKTLH KLSNQNNSYG TRFEYNKESF
- Characteristics
- This is a rabbit polyclonal antibody against NOX4. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human NOX4
- Top Product
- Discover our top product NOX4 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NADPH Oxidase 4 (NOX4)
- Alternative Name
- NOX4 (NOX4 Products)
- Synonyms
- KOX antibody, KOX-1 antibody, RENOX antibody, AI648021 antibody, nox4 antibody, NOX4 antibody, NADPH oxidase 4 antibody, NOX4 antibody, Nox4 antibody, nox4 antibody, PTRG_09562 antibody
- Background
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This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Alias Symbols: NOX4, RENOX,
Protein Interaction Partner: UBC, TLR4,
Protein Size: 271 - Gene ID
- 50507
- Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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