RPS6KA3 antibody (Middle Region)

Catalog No. ABIN5515068

Product Details anti-RPS6KA3 Antibody

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLKRQGYDAA CDIWSLGVLL YTMLTGYTPF ANGPDDTPEE ILARIGSGKF

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RPS6KA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Alternative Name: RPS6KA3 (RPS6KA3 Products)

Synonyms: HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, CLS antibody, HU-3 antibody, ISPK-1 antibody, MAPKAPK1B antibody, MRX19 antibody, RSK2 antibody, S6K-alpha3 antibody, p90-RSK2 antibody, pp90RSK2 antibody, MPK-9 antibody, Rsk2 antibody, RGD1563860 antibody, id:ibd1103 antibody, rps6ka3 antibody, si:ch211-114c12.12 antibody, wu:fk86e02 antibody, zgc:56006 antibody, zgc:158386 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase A3 antibody, ribosomal protein S6 kinase polypeptide 3 antibody, ribosomal protein S6 kinase a, polypeptide 3a antibody, ribosomal protein S6 kinase, polypeptide 3b antibody, RPS6KA1 antibody, RPS6KA3 antibody, Rps6ka3 antibody, rps6ka3a antibody, rps6ka3b antibody

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alias Symbols: CLS, RSK, HU-3, RSK2, MRX19, ISPK-1, p90-RSK2, pp90RSK2, MAPKAPK1B, S6K-alpha3

Protein Size: 167

Gene ID: 6197

NCBI Accession: NM_004586, NP_004577

UniProt: P51812

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades