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PDCD6 antibody (Middle Region)
PDCD6
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDCD6 Antibody
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Target
See all PDCD6 Antibodies
PDCD6
(Programmed Cell Death 6 (PDCD6))
Binding Specificity
All epitopes for PDCD6 antibodies
Middle Region
Reactivity
All reactivities for PDCD6 antibodies
Human
Host
All hosts for PDCD6 antibodies
Rabbit
Clonality
All clonalities for PDCD6 antibodies
Polyclonal
Conjugate
All conjugates for PDCD6 antibodies
This PDCD6 antibody is un-conjugated
Application
All applications for PDCD6 antibodies
Western Blotting (WB)
Sequence
VRSIISMFDR ENKAGVNFSE FTGVWKYITD WQNVFRTYDR DNSGMIDKNE
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PDCD6
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PDCD6
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Target
PDCD6
(Programmed Cell Death 6 (PDCD6))
Alternative Name
PDCD6 (PDCD6 Products )
Synonyms
pdcd6 antibody, MGC52821 antibody, MGC132114 antibody, zgc:63952 antibody, PDCD6 antibody, ALG-2 antibody, PEF1B antibody, AV299538 antibody, Alg2 antibody, MA-3 antibody, PS2 antibody, alg-2 antibody, programmed cell death 6 L homeolog antibody, programmed cell death 6 antibody, pdcd6.L antibody, pdcd6 antibody, PDCD6 antibody, Pdcd6 antibody
Background
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. Alias Symbols: ALG2, ALG-2, PEF1B Protein Size: 167
Gene ID
10016
NCBI Accession
NM_001267556 , NP_001254485
UniProt
O75340
Pathways
Positive Regulation of Endopeptidase Activity
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