RAD52 antibody (Middle Region)

Catalog No. ABIN5515096

Product Details anti-RAD52 Antibody

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD52 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LNNGKFYVGV CAFVRVQLKD GSYHEDVGYG VSEGLKSKAL SLEKARKEAV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD52

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAD52

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Alternative Name: RAD52 (RAD52 Products)

Synonyms: Rad52yh antibody, RAD52 antibody, zgc:112400 antibody, LOC100223085 antibody, MGC115453 antibody, RAD52 homolog, DNA repair protein antibody, RAD52 homolog (S. cerevisiae) antibody, RAD52 homolog, DNA repair protein S homeolog antibody, recombinase antibody, DNA repair and recombination protein, putative antibody, RAD52 protein antibody, RAD52 antibody, Rad52 antibody, rad52 antibody, rad52.S antibody

Background: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Protein Size: 301

Gene ID: 5893

NCBI Accession: NM_001297422, NP_001284348

UniProt: F5GX32

Pathways: DNA Damage Repair