PEX12 antibody (Middle Region)

Catalog No. ABIN5515310

Product Details anti-PEX12 Antibody

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SIMFLVLLPY LKVKLEKLVS SLREEDEYSI HPPSSRWKRF YRAFLAAYPF

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PEX12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEX12

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Alternative Name: PEX12 (PEX12 Products)

Synonyms: zgc:56182 antibody, pex12 antibody, MGC81372 antibody, PEX12 antibody, DDBDRAFT_0186545 antibody, DDBDRAFT_0238076 antibody, DDB_0186545 antibody, DDB_0238076 antibody, LOC100226224 antibody, PAF-3 antibody, PBD3A antibody, Peroxin-12 antibody, AI451906 antibody, peroxisomal biogenesis factor 12 antibody, peroxisomal biogenesis factor 12 L homeolog antibody, RING zinc finger-containing protein antibody, pex12 antibody, PEX12 antibody, pex12.L antibody, Pex12 antibody

Background: This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).

Alias Symbols: PAF-3, PBD3A

Protein Size: 167

Gene ID: 5193

NCBI Accession: NM_000286, NP_000277

UniProt: O00623