BUB1B antibody (N-Term)

Catalog No. ABIN5515394

Product Details anti-BUB1B Antibody

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BUB1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AFEYEIRFYT GNDPLDVWDR YISWTEQNYP QGGKESNMST LLERAVEALQ

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BUB1B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BUB1B

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Alternative Name: BUB1B (BUB1B Products)

Synonyms: BUB1beta antibody, BUBR1 antibody, Bub1A antibody, MAD3L antibody, MVA1 antibody, SSK1 antibody, hBUBR1 antibody, AU045529 antibody, bub1b antibody, BUB1 antibody, BUB1-like antibody, BubR1 antibody, BubRI antibody, CG14030 antibody, CG14030/Bub1 antibody, Dmel\\CG14030 antibody, bub1 antibody, BUB1 mitotic checkpoint serine/threonine kinase B antibody, BUB1B, mitotic checkpoint serine/threonine kinase antibody, BUB1B, mitotic checkpoint serine/threonine kinase L homeolog antibody, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody, Bub1 kinase antibody, BUB1B antibody, Bub1b antibody, bub1b.L antibody, bub1b antibody, Bub1 antibody

Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Alias Symbols: MVA1, SSK1, BUBR1, Bub1A, MAD3L, hBUBR1, BUB1beta

Protein Size: 933

Gene ID: 701

NCBI Accession: NM_001211, NP_001202