SCNN1B antibody (C-Term)

Catalog No. ABIN5515541

Product Details anti-SCNN1B Antibody

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AKSLRQRRAQ ASYAGPPPTV AELVEAHTNF GFQPDTAPRS PNTGPYPSEQ

Characteristics: This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SCNN1B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Alternative Name: SCNN1B (SCNN1B Products)

Synonyms: BESC1 antibody, ENaCb antibody, ENaCbeta antibody, SCNEB antibody, RNENACB antibody, besc1 antibody, betaxENaC antibody, enacb antibody, enacbeta antibody, scnn1b antibody, beta-ENaC antibody, scneb antibody, SCNN1B antibody, BETA-ENAC antibody, sodium channel epithelial 1 beta subunit antibody, sodium channel, non voltage gated 1 beta subunit L homeolog antibody, sodium channel, non voltage gated 1 beta subunit antibody, sodium channel, nonvoltage-gated 1 beta antibody, sodium channel, non voltage gated 1 beta subunit S homeolog antibody, SCNN1B antibody, Scnn1b antibody, scnn1b.L antibody, scnn1b antibody, scnn1b.S antibody

Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

Alias Symbols: BESC1, ENaCb, SCNEB, ENaCbeta

Protein Size: 604

Gene ID: 6338

NCBI Accession: NM_000336, NP_000327

UniProt: P51168