PICK1 antibody (C-Term)

Catalog No. ABIN5515572

Product Details anti-PICK1 Antibody

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PICK1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FPIEVDLAHT TLAYGLNQEE FTDGEEEEEE EDTAAGEPSR DTRGAAGPLD

Characteristics: This is a rabbit polyclonal antibody against PICK1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PICK1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PICK1

Target: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Alternative Name: PICK1 (PICK1 Products)

Synonyms: PICK antibody, PRKCABP antibody, Prkcabp antibody, prkcabp antibody, MGC131295 antibody, PICK1 antibody, DKFZp470L2127 antibody, protein interacting with PRKCA 1 antibody, protein interacting with C kinase 1 antibody, protein interacting with PRKCA 1 L homeolog antibody, PICK1 antibody, Pick1 antibody, pick1 antibody, pick1.L antibody

Background: The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.

Alias Symbols: PICK1, PRKCABP,

Protein Interaction Partner: GRIA2, GPR37, EHD2, GFI1, FXN, ATXN1L, ATXN7L3, UBQLN4, APTX, KLHL24, SACS, CIC, GFI1B, COIL, USP7, ATXN7, PRKCG, ATXN3, GRIK2, UBC, PARK2, GRIP1, PVRL4, PICK1, F11R, LRP2BP, JAM3, GRM7, ASIC1, ASIC2, BTG2, GRM3, EPHB2, PRLHR, PVRL2, EFNB2, GRIA3, EFNB1,

Protein Size: 415

Gene ID: 9463

NCBI Accession: NP_036539

UniProt: Q9NRD5